Found 3 hits for monomerid = 50362987 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50362987
(CHEMBL1945499)Show SMILES CC(C)c1ccc(CCCN(C)C)cc1Nc1ncc2CC(=S)Nc3cc(Cl)ccc3-c2n1 Show InChI InChI=1S/C26H30ClN5S/c1-16(2)20-9-7-17(6-5-11-32(3)4)12-22(20)30-26-28-15-18-13-24(33)29-23-14-19(27)8-10-21(23)25(18)31-26/h7-10,12,14-16H,5-6,11,13H2,1-4H3,(H,29,33)(H,28,30,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of PDGFRb |
J Med Chem 55: 197-208 (2012)
Article DOI: 10.1021/jm2011172 BindingDB Entry DOI: 10.7270/Q21C1XBR |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK3
(Homo sapiens (Human)) | BDBM50362987
(CHEMBL1945499)Show SMILES CC(C)c1ccc(CCCN(C)C)cc1Nc1ncc2CC(=S)Nc3cc(Cl)ccc3-c2n1 Show InChI InChI=1S/C26H30ClN5S/c1-16(2)20-9-7-17(6-5-11-32(3)4)12-22(20)30-26-28-15-18-13-24(33)29-23-14-19(27)8-10-21(23)25(18)31-26/h7-10,12,14-16H,5-6,11,13H2,1-4H3,(H,29,33)(H,28,30,31) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of PLK3 |
J Med Chem 55: 197-208 (2012)
Article DOI: 10.1021/jm2011172 BindingDB Entry DOI: 10.7270/Q21C1XBR |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50362987
(CHEMBL1945499)Show SMILES CC(C)c1ccc(CCCN(C)C)cc1Nc1ncc2CC(=S)Nc3cc(Cl)ccc3-c2n1 Show InChI InChI=1S/C26H30ClN5S/c1-16(2)20-9-7-17(6-5-11-32(3)4)12-22(20)30-26-28-15-18-13-24(33)29-23-14-19(27)8-10-21(23)25(18)31-26/h7-10,12,14-16H,5-6,11,13H2,1-4H3,(H,29,33)(H,28,30,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description Inhibition of KDR |
J Med Chem 55: 197-208 (2012)
Article DOI: 10.1021/jm2011172 BindingDB Entry DOI: 10.7270/Q21C1XBR |
More data for this Ligand-Target Pair | |