Found 3 hits for monomerid = 50363339 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50363339
(CHEMBL1946024)Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6]-c2ccc(F)cc2)-[#6]-[#6]-1)\c1ccc(-[#7]-[#6](=O)-[#8]-[#6])cc1 Show InChI InChI=1S/C32H36FN3O3/c1-4-36(5-2)31(37)27-10-8-24(9-11-27)30(25-12-16-29(17-13-25)34-32(38)39-3)26-18-20-35(21-19-26)22-23-6-14-28(33)15-7-23/h6-17H,4-5,18-22H2,1-3H3,(H,34,38) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of radiolabeled iodinated deltorphin 2 from delta opioid receptor expressed in HEK293 cell membranes |
Bioorg Med Chem Lett 22: 1174-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.089 BindingDB Entry DOI: 10.7270/Q2FF3STJ |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50363339
(CHEMBL1946024)Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6]-c2ccc(F)cc2)-[#6]-[#6]-1)\c1ccc(-[#7]-[#6](=O)-[#8]-[#6])cc1 Show InChI InChI=1S/C32H36FN3O3/c1-4-36(5-2)31(37)27-10-8-24(9-11-27)30(25-12-16-29(17-13-25)34-32(38)39-3)26-18-20-35(21-19-26)22-23-6-14-28(33)15-7-23/h6-17H,4-5,18-22H2,1-3H3,(H,34,38) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
Bioorg Med Chem Lett 22: 1174-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.089 BindingDB Entry DOI: 10.7270/Q2FF3STJ |
More data for this Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50363339
(CHEMBL1946024)Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#7](-[#6]-c2ccc(F)cc2)-[#6]-[#6]-1)\c1ccc(-[#7]-[#6](=O)-[#8]-[#6])cc1 Show InChI InChI=1S/C32H36FN3O3/c1-4-36(5-2)31(37)27-10-8-24(9-11-27)30(25-12-16-29(17-13-25)34-32(38)39-3)26-18-20-35(21-19-26)22-23-6-14-28(33)15-7-23/h6-17H,4-5,18-22H2,1-3H3,(H,34,38) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Pharmaceuticals
Curated by ChEMBL
| Assay Description Displacement of radiolabeled FK33-824 from mu opioid receptor expressed in HEK293 cell membranes |
Bioorg Med Chem Lett 22: 1174-8 (2012)
Article DOI: 10.1016/j.bmcl.2011.11.089 BindingDB Entry DOI: 10.7270/Q2FF3STJ |
More data for this Ligand-Target Pair | |