BDBM50363851 CHEMBL1945938

SMILES: Fc1cc2[nH]cc(-c3nc4ccccc4nc3Cl)c2cc1F

InChI Key: InChIKey=FFXWDDMBUMVVFL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50363851   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chorismate mutase (MTB CM) (Mycobacterium tuberculosis H37Rv)	BDBM50363851 (CHEMBL1945938) Show SMILES Fc1cc2[nH]cc(-c3nc4ccccc4nc3Cl)c2cc1F Show InChI InChI=1S/C16H8ClF2N3/c17-16-15(21-12-3-1-2-4-13(12)22-16)9-7-20-14-6-11(19)10(18)5-8(9)14/h1-7,20H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hyderabad Campus Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis chorismate mutase expressed in Escherichia coli BL21 assessed as conversion of chorismate to prephenate afte...				Bioorg Med Chem 20: 1711-22 (2012) Article DOI: 10.1016/j.bmc.2012.01.012 BindingDB Entry DOI: 10.7270/Q2222V6Q
					More data for this Ligand-Target Pair