BDBM50363914 CHEMBL1946938

SMILES: CCc1cc2c(ccc(OC)n2c1)C1=NNC(=O)CC1C

InChI Key: InChIKey=KZEQZANCHVGFLX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50363914 (CHEMBL1946938) Show SMILES CCc1cc2c(ccc(OC)n2c1)C1=NNC(=O)CC1C |t:15| Show InChI InChI=1S/C16H19N3O2/c1-4-11-8-13-12(5-6-15(21-3)19(13)9-11)16-10(2)7-14(20)17-18-16/h5-6,8-10H,4,7H2,1-3H3,(H,17,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDE4B catalytic domain				Bioorg Med Chem 20: 1644-58 (2012) Article DOI: 10.1016/j.bmc.2012.01.033 BindingDB Entry DOI: 10.7270/Q2DB829P
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (PDE3) (Homo sapiens (Human))	BDBM50363914 (CHEMBL1946938) Show SMILES CCc1cc2c(ccc(OC)n2c1)C1=NNC(=O)CC1C |t:15| Show InChI InChI=1S/C16H19N3O2/c1-4-11-8-13-12(5-6-15(21-3)19(13)9-11)16-10(2)7-14(20)17-18-16/h5-6,8-10H,4,7H2,1-3H3,(H,17,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human PDE3A catalytic domain				Bioorg Med Chem 20: 1644-58 (2012) Article DOI: 10.1016/j.bmc.2012.01.033 BindingDB Entry DOI: 10.7270/Q2DB829P
					More data for this Ligand-Target Pair