BDBM50364253 CHEMBL1952085

SMILES: Clc1ccc(cc1)C(OC1CN(C1)C(=O)N1CCCC1)c1cccnc1Cl

InChI Key: InChIKey=CIAIGDUPLJRKJZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50364253 (CHEMBL1952085) Show SMILES Clc1ccc(cc1)C(OC1CN(C1)C(=O)N1CCCC1)c1cccnc1Cl Show InChI InChI=1S/C20H21Cl2N3O2/c21-15-7-5-14(6-8-15)18(17-4-3-9-23-19(17)22)27-16-12-25(13-16)20(26)24-10-1-2-11-24/h3-9,16,18H,1-2,10-13H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd Curated by ChEMBL					Assay Description Inhibition of rat FAAH using 7-amino-4-methylcoumarine amide as substrate preincubated for 1 hr by fluorimetry				Bioorg Med Chem Lett 22: 901-6 (2012) Article DOI: 10.1016/j.bmcl.2011.12.032 BindingDB Entry DOI: 10.7270/Q2D79BVH
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50364253 (CHEMBL1952085) Show SMILES Clc1ccc(cc1)C(OC1CN(C1)C(=O)N1CCCC1)c1cccnc1Cl Show InChI InChI=1S/C20H21Cl2N3O2/c21-15-7-5-14(6-8-15)18(17-4-3-9-23-19(17)22)27-16-12-25(13-16)20(26)24-10-1-2-11-24/h3-9,16,18H,1-2,10-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis (R&D) Ltd Curated by ChEMBL					Assay Description Inhibition of human FAAH expressed in CHO cells using 7-amino-4-methylcoumarine amide as substrate preincubated for 1 hr by fluorimetry				Bioorg Med Chem Lett 22: 901-6 (2012) Article DOI: 10.1016/j.bmcl.2011.12.032 BindingDB Entry DOI: 10.7270/Q2D79BVH
					More data for this Ligand-Target Pair