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SMILES: Clc1ccc(cc1)C(OC1CN(C1)C(=O)N1Cc2ccccc2C1)c1cccnc1Cl

InChI Key: InChIKey=NOCFJFOFYJSXQM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364279   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50364279
PNG
(CHEMBL1952277)
Show SMILES Clc1ccc(cc1)C(OC1CN(C1)C(=O)N1Cc2ccccc2C1)c1cccnc1Cl
Show InChI InChI=1S/C24H21Cl2N3O2/c25-19-9-7-16(8-10-19)22(21-6-3-11-27-23(21)26)31-20-14-29(15-20)24(30)28-12-17-4-1-2-5-18(17)13-28/h1-11,20,22H,12-15H2
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.99E+3n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Inhibition of rat FAAH using 7-amino-4-methylcoumarine amide as substrate preincubated for 1 hr by fluorimetry


Bioorg Med Chem Lett 22: 901-6 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.032
BindingDB Entry DOI: 10.7270/Q2D79BVH
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50364279
PNG
(CHEMBL1952277)
Show SMILES Clc1ccc(cc1)C(OC1CN(C1)C(=O)N1Cc2ccccc2C1)c1cccnc1Cl
Show InChI InChI=1S/C24H21Cl2N3O2/c25-19-9-7-16(8-10-19)22(21-6-3-11-27-23(21)26)31-20-14-29(15-20)24(30)28-12-17-4-1-2-5-18(17)13-28/h1-11,20,22H,12-15H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.47E+4n/an/an/an/an/an/a



Vernalis (R&D) Ltd

Curated by ChEMBL


Assay Description
Inhibition of human FAAH expressed in CHO cells using 7-amino-4-methylcoumarine amide as substrate preincubated for 1 hr by fluorimetry


Bioorg Med Chem Lett 22: 901-6 (2012)


Article DOI: 10.1016/j.bmcl.2011.12.032
BindingDB Entry DOI: 10.7270/Q2D79BVH
More data for this
Ligand-Target Pair