BDBM50364294 CHEMBL1952306

SMILES: CCCCCc1cccc(c1)B1OC(C)(C)C(C)(C)O1

InChI Key: InChIKey=ANOKHFHSDKTWHA-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50364294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM50364294 (CHEMBL1952306) Show SMILES CCCCCc1cccc(c1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C17H27BO2/c1-6-7-8-10-14-11-9-12-15(13-14)18-19-16(2,3)17(4,5)20-18/h9,11-13H,6-8,10H2,1-5H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364294 (CHEMBL1952306) Show SMILES CCCCCc1cccc(c1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C17H27BO2/c1-6-7-8-10-14-11-9-12-15(13-14)18-19-16(2,3)17(4,5)20-18/h9,11-13H,6-8,10H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50364294 (CHEMBL1952306) Show SMILES CCCCCc1cccc(c1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C17H27BO2/c1-6-7-8-10-14-11-9-12-15(13-14)18-19-16(2,3)17(4,5)20-18/h9,11-13H,6-8,10H2,1-5H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase overexpressed in HUVEC cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substr...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364294 (CHEMBL1952306) Show SMILES CCCCCc1cccc(c1)B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C17H27BO2/c1-6-7-8-10-14-11-9-12-15(13-14)18-19-16(2,3)17(4,5)20-18/h9,11-13H,6-8,10H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair