BDBM50364297 CHEMBL1952309
SMILES: CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccco1
InChI Key: InChIKey=PUCSCLCOEROOCP-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelial lipase (Homo sapiens (Human)) | BDBM50364297 (CHEMBL1952309) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tufts University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human endothelial lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay | Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lipoprotein lipase (Homo sapiens (Human)) | BDBM50364297 (CHEMBL1952309) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tufts University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate... | Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelial lipase (Homo sapiens (Human)) | BDBM50364297 (CHEMBL1952309) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tufts University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human endothelial lipase overexpressed in HUVEC cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substr... | Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lipoprotein lipase (Homo sapiens (Human)) | BDBM50364297 (CHEMBL1952309) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tufts University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay | Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N | |||||||||||
More data for this Ligand-Target Pair |