BDBM50364300 CHEMBL1952312

SMILES: CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccsc1

InChI Key: InChIKey=XKGSZASBTMAIMT-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50364300   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM50364300 (CHEMBL1952312) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccsc1 Show InChI InChI=1S/C16H19BO2S/c1-15(2)16(3,4)19-17(18-15)14-7-5-12(6-8-14)13-9-10-20-11-13/h5-11H,1-4H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364300 (CHEMBL1952312) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccsc1 Show InChI InChI=1S/C16H19BO2S/c1-15(2)16(3,4)19-17(18-15)14-7-5-12(6-8-14)13-9-10-20-11-13/h5-11H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed in HEK293 cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substrate...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50364300 (CHEMBL1952312) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccsc1 Show InChI InChI=1S/C16H19BO2S/c1-15(2)16(3,4)19-17(18-15)14-7-5-12(6-8-14)13-9-10-20-11-13/h5-11H,1-4H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human endothelial lipase overexpressed in HUVEC cells using bis-BD-PC and mono-BD-TG as substrate incubated for 10 mins prior to substr...				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50364300 (CHEMBL1952312) Show SMILES CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccsc1 Show InChI InChI=1S/C16H19BO2S/c1-15(2)16(3,4)19-17(18-15)14-7-5-12(6-8-14)13-9-10-20-11-13/h5-11H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human lipoprotein lipase expressed using recombinant adenovirus using glycerol-tri[9,10(n)-3H]oleate after 1 hr by vesicle assay				Bioorg Med Chem Lett 22: 1397-401 (2012) Article DOI: 10.1016/j.bmcl.2011.12.043 BindingDB Entry DOI: 10.7270/Q28G8M5N
					More data for this Ligand-Target Pair