BDBM50364393 CHEMBL1950309

SMILES: C[C@H](NC(=O)CCN1CCN(CC1)c1cccc(F)c1)c1nc2cc(Cl)c(Cl)cc2[nH]1

InChI Key: InChIKey=WZDDRSQDYCTGTA-AWEZNQCLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Mus musculus)	BDBM50364393 (CHEMBL1950309) Show SMILES C[C@H](NC(=O)CCN1CCN(CC1)c1cccc(F)c1)c1nc2cc(Cl)c(Cl)cc2[nH]1 |r| Show InChI InChI=1S/C22H24Cl2FN5O/c1-14(22-27-19-12-17(23)18(24)13-20(19)28-22)26-21(31)5-6-29-7-9-30(10-8-29)16-4-2-3-15(25)11-16/h2-4,11-14H,5-10H2,1H3,(H,26,31)(H,27,28)/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PrCP-mediated angiotensin3 cleavage in mouse plasma using Mca-Ala-Lys-Dnp as substrate for 8 mins by LC/MS analysis				Bioorg Med Chem Lett 22: 1774-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.064 BindingDB Entry DOI: 10.7270/Q27H1K28
					More data for this Ligand-Target Pair
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50364393 (CHEMBL1950309) Show SMILES C[C@H](NC(=O)CCN1CCN(CC1)c1cccc(F)c1)c1nc2cc(Cl)c(Cl)cc2[nH]1 |r| Show InChI InChI=1S/C22H24Cl2FN5O/c1-14(22-27-19-12-17(23)18(24)13-20(19)28-22)26-21(31)5-6-29-7-9-30(10-8-29)16-4-2-3-15(25)11-16/h2-4,11-14H,5-10H2,1H3,(H,26,31)(H,27,28)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assay				Bioorg Med Chem Lett 22: 1774-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.064 BindingDB Entry DOI: 10.7270/Q27H1K28
					More data for this Ligand-Target Pair