BDBM50364536 CHEMBL1950879

SMILES: CCCc1cc(n[nH]1)-c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1

InChI Key: InChIKey=QJTJQXIBBHMOBJ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50364536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50364536 (CHEMBL1950879) Show SMILES CCCc1cc(n[nH]1)-c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C27H25Cl2N3O6S/c1-3-4-19-15-21(31-30-19)17-6-9-23(38-24-8-5-16(12-27(33)34)11-25(24)37-2)22(13-17)32-39(35,36)26-10-7-18(28)14-20(26)29/h5-11,13-15,32H,3-4,12H2,1-2H3,(H,30,31)(H,33,34)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human DP receptor expressed in HEK293 cells by scintillation counting in presence of 0.5% BSA				Bioorg Med Chem Lett 22: 1686-9 (2012) Article DOI: 10.1016/j.bmcl.2011.12.107 BindingDB Entry DOI: 10.7270/Q2B858MR
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50364536 (CHEMBL1950879) Show SMILES CCCc1cc(n[nH]1)-c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C27H25Cl2N3O6S/c1-3-4-19-15-21(31-30-19)17-6-9-23(38-24-8-5-16(12-27(33)34)11-25(24)37-2)22(13-17)32-39(35,36)26-10-7-18(28)14-20(26)29/h5-11,13-15,32H,3-4,12H2,1-2H3,(H,30,31)(H,33,34)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human DP receptor expressed in HEK293 cells by scintillation counting in presence of 0.5% BSA				Bioorg Med Chem Lett 22: 1686-9 (2012) Article DOI: 10.1016/j.bmcl.2011.12.107 BindingDB Entry DOI: 10.7270/Q2B858MR
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50364536 (CHEMBL1950879) Show SMILES CCCc1cc(n[nH]1)-c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C27H25Cl2N3O6S/c1-3-4-19-15-21(31-30-19)17-6-9-23(38-24-8-5-16(12-27(33)34)11-25(24)37-2)22(13-17)32-39(35,36)26-10-7-18(28)14-20(26)29/h5-11,13-15,32H,3-4,12H2,1-2H3,(H,30,31)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells by scintillation counting in presence of 50% plasma				Bioorg Med Chem Lett 22: 1686-9 (2012) Article DOI: 10.1016/j.bmcl.2011.12.107 BindingDB Entry DOI: 10.7270/Q2B858MR
					More data for this Ligand-Target Pair
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50364536 (CHEMBL1950879) Show SMILES CCCc1cc(n[nH]1)-c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C27H25Cl2N3O6S/c1-3-4-19-15-21(31-30-19)17-6-9-23(38-24-8-5-16(12-27(33)34)11-25(24)37-2)22(13-17)32-39(35,36)26-10-7-18(28)14-20(26)29/h5-11,13-15,32H,3-4,12H2,1-2H3,(H,30,31)(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells by scintillation counting in presence of 0.5% BSA				Bioorg Med Chem Lett 22: 1686-9 (2012) Article DOI: 10.1016/j.bmcl.2011.12.107 BindingDB Entry DOI: 10.7270/Q2B858MR
					More data for this Ligand-Target Pair