BDBM50364677 CHEMBL1951466

SMILES: FC(F)(F)Oc1ccc(CN2CCC3(CC2)OC(c2ccccc32)c2ccc(Cl)cn2)cc1

InChI Key: InChIKey=WOZKQSJEEDBCPZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364677   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Mus musculus)	BDBM50364677 (CHEMBL1951466) Show SMILES FC(F)(F)Oc1ccc(CN2CCC3(CC2)OC(c2ccccc32)c2ccc(Cl)cn2)cc1 Show InChI InChI=1S/C25H22ClF3N2O2/c26-18-7-10-22(30-15-18)23-20-3-1-2-4-21(20)24(33-23)11-13-31(14-12-24)16-17-5-8-19(9-6-17)32-25(27,28)29/h1-10,15,23H,11-14,16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse PrCP				Bioorg Med Chem Lett 22: 1550-6 (2012) Article DOI: 10.1016/j.bmcl.2012.01.002 BindingDB Entry DOI: 10.7270/Q2JS9QXQ
					More data for this Ligand-Target Pair
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50364677 (CHEMBL1951466) Show SMILES FC(F)(F)Oc1ccc(CN2CCC3(CC2)OC(c2ccccc32)c2ccc(Cl)cn2)cc1 Show InChI InChI=1S/C25H22ClF3N2O2/c26-18-7-10-22(30-15-18)23-20-3-1-2-4-21(20)24(33-23)11-13-31(14-12-24)16-17-5-8-19(9-6-17)32-25(27,28)29/h1-10,15,23H,11-14,16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human PrCP				Bioorg Med Chem Lett 22: 1550-6 (2012) Article DOI: 10.1016/j.bmcl.2012.01.002 BindingDB Entry DOI: 10.7270/Q2JS9QXQ
					More data for this Ligand-Target Pair