BDBM50364680 CHEMBL1951469
SMILES: FC(F)(F)Oc1ccc(CN2CCC3(CC2)OC(c2cccnc32)c2cc(Cl)ccn2)cc1
InChI Key: InChIKey=QJAHKJMEFFSZQQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50364680 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lysosomal Pro-X carboxypeptidase
(Mus musculus) | BDBM50364680
(CHEMBL1951469)Show SMILES FC(F)(F)Oc1ccc(CN2CCC3(CC2)OC(c2cccnc32)c2cc(Cl)ccn2)cc1 Show InChI InChI=1S/C24H21ClF3N3O2/c25-17-7-11-29-20(14-17)21-19-2-1-10-30-22(19)23(33-21)8-12-31(13-9-23)15-16-3-5-18(6-4-16)32-24(26,27)28/h1-7,10-11,14,21H,8-9,12-13,15H2 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse PrCP |
Bioorg Med Chem Lett 22: 1550-6 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.002
BindingDB Entry DOI: 10.7270/Q2JS9QXQ |
More data for this
Ligand-Target Pair | |
Prolylcarboxypeptidase (PRCP)
(Homo sapiens (Human)) | BDBM50364680
(CHEMBL1951469)Show SMILES FC(F)(F)Oc1ccc(CN2CCC3(CC2)OC(c2cccnc32)c2cc(Cl)ccn2)cc1 Show InChI InChI=1S/C24H21ClF3N3O2/c25-17-7-11-29-20(14-17)21-19-2-1-10-30-22(19)23(33-21)8-12-31(13-9-23)15-16-3-5-18(6-4-16)32-24(26,27)28/h1-7,10-11,14,21H,8-9,12-13,15H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human PrCP |
Bioorg Med Chem Lett 22: 1550-6 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.002
BindingDB Entry DOI: 10.7270/Q2JS9QXQ |
More data for this
Ligand-Target Pair | |
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