null

SMILES: Cc1ccc(cc1)-n1ccc2c(sc3ncnc(NC4CC4)c23)c1=O

InChI Key: InChIKey=IZXQPAIBAFLWPA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364718   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50364718 (CHEMBL1951890) Show SMILES Cc1ccc(cc1)-n1ccc2c(sc3ncnc(NC4CC4)c23)c1=O Show InChI InChI=1S/C19H16N4OS/c1-11-2-6-13(7-3-11)23-9-8-14-15-17(22-12-4-5-12)20-10-21-18(15)25-16(14)19(23)24/h2-3,6-10,12H,4-5H2,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat metabotropic glutamate receptor 1				Bioorg Med Chem Lett 22: 1575-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.131 BindingDB Entry DOI: 10.7270/Q2F19063
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50364718 (CHEMBL1951890) Show SMILES Cc1ccc(cc1)-n1ccc2c(sc3ncnc(NC4CC4)c23)c1=O Show InChI InChI=1S/C19H16N4OS/c1-11-2-6-13(7-3-11)23-9-8-14-15-17(22-12-4-5-12)20-10-21-18(15)25-16(14)19(23)24/h2-3,6-10,12H,4-5H2,1H3,(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human metabotropic glutamate receptor 1				Bioorg Med Chem Lett 22: 1575-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.131 BindingDB Entry DOI: 10.7270/Q2F19063
					More data for this Ligand-Target Pair