BDBM50364735 CHEMBL1951674

SMILES: COc1ccc(c(C)c1)-n1ccc2c3c(OC)ccnc3sc2c1=O

InChI Key: InChIKey=SAUGHCXILOWEQR-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364735   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (RAT)	BDBM50364735 (CHEMBL1951674) Show SMILES COc1ccc(c(C)c1)-n1ccc2c3c(OC)ccnc3sc2c1=O Show InChI InChI=1S/C19H16N2O3S/c1-11-10-12(23-2)4-5-14(11)21-9-7-13-16-15(24-3)6-8-20-18(16)25-17(13)19(21)22/h4-10H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat metabotropic glutamate receptor 1				Bioorg Med Chem Lett 22: 1575-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.131 BindingDB Entry DOI: 10.7270/Q2F19063
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50364735 (CHEMBL1951674) Show SMILES COc1ccc(c(C)c1)-n1ccc2c3c(OC)ccnc3sc2c1=O Show InChI InChI=1S/C19H16N2O3S/c1-11-10-12(23-2)4-5-14(11)21-9-7-13-16-15(24-3)6-8-20-18(16)25-17(13)19(21)22/h4-10H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human metabotropic glutamate receptor 1				Bioorg Med Chem Lett 22: 1575-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.131 BindingDB Entry DOI: 10.7270/Q2F19063
					More data for this Ligand-Target Pair