BDBM50364736 CHEMBL1951675

SMILES: CCc1ccc(cc1)-n1ccc2c(sc3nccc(OC)c23)c1=O

InChI Key: InChIKey=GFFRNKSYOJSMMI-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364736   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (RAT)	BDBM50364736 (CHEMBL1951675) Show SMILES CCc1ccc(cc1)-n1ccc2c(sc3nccc(OC)c23)c1=O Show InChI InChI=1S/C19H16N2O2S/c1-3-12-4-6-13(7-5-12)21-11-9-14-16-15(23-2)8-10-20-18(16)24-17(14)19(21)22/h4-11H,3H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at rat metabotropic glutamate receptor 1				Bioorg Med Chem Lett 22: 1575-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.131 BindingDB Entry DOI: 10.7270/Q2F19063
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50364736 (CHEMBL1951675) Show SMILES CCc1ccc(cc1)-n1ccc2c(sc3nccc(OC)c23)c1=O Show InChI InChI=1S/C19H16N2O2S/c1-3-12-4-6-13(7-5-12)21-11-9-14-16-15(23-2)8-10-20-18(16)24-17(14)19(21)22/h4-11H,3H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human metabotropic glutamate receptor 1				Bioorg Med Chem Lett 22: 1575-8 (2012) Article DOI: 10.1016/j.bmcl.2011.12.131 BindingDB Entry DOI: 10.7270/Q2F19063
					More data for this Ligand-Target Pair