BDBM50364806 CHEMBL1952328

SMILES: Oc1ccc(cc1)-c1cnc2ccc(NCc3ccc(F)cc3)nn12

InChI Key: InChIKey=IAFJBBRUTHQHRQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364806   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50364806 (CHEMBL1952328) Show SMILES Oc1ccc(cc1)-c1cnc2ccc(NCc3ccc(F)cc3)nn12 Show InChI InChI=1S/C19H15FN4O/c20-15-5-1-13(2-6-15)11-21-18-9-10-19-22-12-17(24(19)23-18)14-3-7-16(25)8-4-14/h1-10,12,25H,11H2,(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Rheinische Friedrich-Wilhelms-Universit£t Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin)				J Med Chem 60: 1238-1246 (2017) BindingDB Entry DOI: 10.7270/Q2KK9F10
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50364806 (CHEMBL1952328) Show SMILES Oc1ccc(cc1)-c1cnc2ccc(NCc3ccc(F)cc3)nn12 Show InChI InChI=1S/C19H15FN4O/c20-15-5-1-13(2-6-15)11-21-18-9-10-19-22-12-17(24(19)23-18)14-3-7-16(25)8-4-14/h1-10,12,25H,11H2,(H,21,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Spanish National Cancer Research Centre (CNIO) Curated by ChEMBL					Assay Description Inhibition of PIM1				Bioorg Med Chem Lett 22: 1591-7 (2012) Article DOI: 10.1016/j.bmcl.2011.12.130 BindingDB Entry DOI: 10.7270/Q21R6QZ1
					More data for this Ligand-Target Pair