BDBM50364952 CHEMBL1950337

SMILES: CC1CCN(CC1)C(=O)c1ccc2n(CC=C)c3CCN(Cc4cccnc4)Cc3c2c1

InChI Key: InChIKey=YZXHMXKDZSVFQN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50364952   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50364952 (CHEMBL1950337) Show SMILES CC1CCN(CC1)C(=O)c1ccc2n(CC=C)c3CCN(Cc4cccnc4)Cc3c2c1 Show InChI InChI=1S/C27H32N4O/c1-3-12-31-25-7-6-22(27(32)30-14-8-20(2)9-15-30)16-23(25)24-19-29(13-10-26(24)31)18-21-5-4-11-28-17-21/h3-7,11,16-17,20H,1,8-10,12-15,18-19H2,2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.40E+4	n/a	n/a	n/a	n/a
AstraZeneca R&D Montreal Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in HEK293 EBNA cells by [35S]GTPgamma binding assay				Bioorg Med Chem Lett 22: 1619-24 (2012) Article DOI: 10.1016/j.bmcl.2011.12.124 BindingDB Entry DOI: 10.7270/Q24J0FJX
					More data for this Ligand-Target Pair