BDBM50365102 CHEMBL1951191

SMILES: C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)NP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3cnc4c3nc(N)[nH]c4=O)[C@@H](O)[C@H]2O)c2nc(N)[n-]c(=O)c12

InChI Key: InChIKey=GSOLLBGXRSSEFN-INFSMZHSSA-K

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus)	BDBM50365102 (CHEMBL1951191) Show SMILES C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)NP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3cnc4c3nc(N)[nH]c4=O)[C@@H](O)[C@H]2O)c2nc(N)[n-]c(=O)c12 |r| Show InChI InChI=1S/C21H30N11O17P3/c1-30-5-32(15-9(30)17(38)28-21(23)26-15)19-13(36)11(34)7(48-19)3-46-52(43,44)49-51(41,42)29-50(39,40)45-2-6-10(33)12(35)18(47-6)31-4-24-8-14(31)25-20(22)27-16(8)37/h4-7,10-13,18-19,33-36H,2-3H2,1H3,(H9-,22,23,25,26,27,28,29,37,38,39,40,41,42,43,44)/p-3/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate by luciferase reporter gene assay				Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Oryctolagus cuniculus)	BDBM50365102 (CHEMBL1951191) Show SMILES C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)NP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3cnc4c3nc(N)[nH]c4=O)[C@@H](O)[C@H]2O)c2nc(N)[n-]c(=O)c12 |r| Show InChI InChI=1S/C21H30N11O17P3/c1-30-5-32(15-9(30)17(38)28-21(23)26-15)19-13(36)11(34)7(48-19)3-46-52(43,44)49-51(41,42)29-50(39,40)45-2-6-10(33)12(35)18(47-6)31-4-24-8-14(31)25-20(22)27-16(8)37/h4-7,10-13,18-19,33-36H,2-3H2,1H3,(H9-,22,23,25,26,27,28,29,37,38,39,40,41,42,43,44)/p-3/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Warsaw Curated by ChEMBL					Assay Description Inhibition of eIF4E-mediated mRNA translation in rabbit reticulocyte lysate pre-incubated for 60 mins prior to mRNA addition by luciferase reporter g...				Bioorg Med Chem 20: 1699-710 (2012) Article DOI: 10.1016/j.bmc.2012.01.013 BindingDB Entry DOI: 10.7270/Q2ZW1MC1
					More data for this Ligand-Target Pair