BDBM50365165 CHEMBL1950017

SMILES: Cc1ccnc(c1)C(=O)c1[nH]c2ccc(F)cc2c1CC(O)=O

InChI Key: InChIKey=DNIKRHXQZCTYOD-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50365165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50365165 (CHEMBL1950017) Show SMILES Cc1ccnc(c1)C(=O)c1[nH]c2ccc(F)cc2c1CC(O)=O Show InChI InChI=1S/C17H13FN2O3/c1-9-4-5-19-14(6-9)17(23)16-12(8-15(21)22)11-7-10(18)2-3-13(11)20-16/h2-7,20H,8H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-1-mediated TXB2 production in human platelets preincubated for 20 mins prior A23187 stimulation measured after 15 mins by RIA				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50365165 (CHEMBL1950017) Show SMILES Cc1ccnc(c1)C(=O)c1[nH]c2ccc(F)cc2c1CC(O)=O Show InChI InChI=1S/C17H13FN2O3/c1-9-4-5-19-14(6-9)17(23)16-12(8-15(21)22)11-7-10(18)2-3-13(11)20-16/h2-7,20H,8H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-2-mediated PGE2 production in LPS-induced human whole blood after 24 hrs by RIA				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50365165 (CHEMBL1950017) Show SMILES Cc1ccnc(c1)C(=O)c1[nH]c2ccc(F)cc2c1CC(O)=O Show InChI InChI=1S/C17H13FN2O3/c1-9-4-5-19-14(6-9)17(23)16-12(8-15(21)22)11-7-10(18)2-3-13(11)20-16/h2-7,20H,8H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIA				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50365165 (CHEMBL1950017) Show SMILES Cc1ccnc(c1)C(=O)c1[nH]c2ccc(F)cc2c1CC(O)=O Show InChI InChI=1S/C17H13FN2O3/c1-9-4-5-19-14(6-9)17(23)16-12(8-15(21)22)11-7-10(18)2-3-13(11)20-16/h2-7,20H,8H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
					More data for this Ligand-Target Pair