null

SMILES: CCOc1cnc(cc1CC)C(=O)c1[nH]c2cc(Cl)ccc2c1CC(O)=O

InChI Key: InChIKey=FMIMEKPJOIWECI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50365169 (CHEMBL1950021) Show SMILES CCOc1cnc(cc1CC)C(=O)c1[nH]c2cc(Cl)ccc2c1CC(O)=O Show InChI InChI=1S/C20H19ClN2O4/c1-3-11-7-16(22-10-17(11)27-4-2)20(26)19-14(9-18(24)25)13-6-5-12(21)8-15(13)23-19/h5-8,10,23H,3-4,9H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-1-mediated TXB2 production in human whole blood after 15 mins post A23187 stimulation by RIA				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50365169 (CHEMBL1950021) Show SMILES CCOc1cnc(cc1CC)C(=O)c1[nH]c2cc(Cl)ccc2c1CC(O)=O Show InChI InChI=1S/C20H19ClN2O4/c1-3-11-7-16(22-10-17(11)27-4-2)20(26)19-14(9-18(24)25)13-6-5-12(21)8-15(13)23-19/h5-8,10,23H,3-4,9H2,1-2H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	598	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX-2-mediated 6-keto-PGF1alpha production in IL-1beta-induced HUVEC preincubated for 20 mins prior A23187 stimulation measured after 1...				Eur J Med Chem 50: 179-95 (2012) Article DOI: 10.1016/j.ejmech.2012.01.053 BindingDB Entry DOI: 10.7270/Q2B27VR8
					More data for this Ligand-Target Pair