BDBM50365574 CHEMBL1957819

SMILES: Fc1ccc(CCN2CCN(CC2)C(=O)c2cccn3cc(nc23)C#N)c(F)c1

InChI Key: InChIKey=OOFQSGORGXYAIN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50365574 (CHEMBL1957819) Show SMILES Fc1ccc(CCN2CCN(CC2)C(=O)c2cccn3cc(nc23)C#N)c(F)c1 Show InChI InChI=1S/C21H19F2N5O/c22-16-4-3-15(19(23)12-16)5-7-26-8-10-27(11-9-26)21(29)18-2-1-6-28-14-17(13-24)25-20(18)28/h1-4,6,12,14H,5,7-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-DOI from recombinant human 5HT2A receptor				Bioorg Med Chem Lett 22: 1870-3 (2012) Article DOI: 10.1016/j.bmcl.2012.01.080 BindingDB Entry DOI: 10.7270/Q2XP75D0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50365574 (CHEMBL1957819) Show SMILES Fc1ccc(CCN2CCN(CC2)C(=O)c2cccn3cc(nc23)C#N)c(F)c1 Show InChI InChI=1S/C21H19F2N5O/c22-16-4-3-15(19(23)12-16)5-7-26-8-10-27(11-9-26)21(29)18-2-1-6-28-14-17(13-24)25-20(18)28/h1-4,6,12,14H,5,7-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-DOI from recombinant human 5HT2C receptor				Bioorg Med Chem Lett 22: 1870-3 (2012) Article DOI: 10.1016/j.bmcl.2012.01.080 BindingDB Entry DOI: 10.7270/Q2XP75D0
					More data for this Ligand-Target Pair