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SMILES: CN1CCN(CC1)c1ccc(Nc2ncc(-c3cc[nH]c(=O)c3)n3ncnc23)cc1

InChI Key: InChIKey=ULADOTYNHIXXPX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365802   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 5


(Homo sapiens (Human))		BDBM50365802
PNG
(CHEMBL1956683)
Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(-c3cc[nH]c(=O)c3)n3ncnc23)cc1
Show InChI InChI=1S/C21H22N8O/c1-27-8-10-28(11-9-27)17-4-2-16(3-5-17)26-20-21-24-14-25-29(21)18(13-23-20)15-6-7-22-19(30)12-15/h2-7,12-14H,8-11H2,1H3,(H,22,30)(H,23,26)
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n/an/a 3.73E+3n/an/an/an/an/an/a



Galapagos NV

Curated by ChEMBL


Assay Description
Inhibition of MAPKAPK5

Bioorg Med Chem Lett 22: 2266-70 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.077
BindingDB Entry DOI: 10.7270/Q2CR5TT6
More data for this
Ligand-Target Pair