BDBM50365819 CHEMBL1956998
SMILES: CC(C)N1CCC[C@H](Cn2c(C)nc3cnc(Oc4ccc(F)cc4)cc3c2=O)C1
InChI Key: InChIKey=DAFSCUDUKCWLDL-KRWDZBQOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50365819 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Ghrelin receptor
(Homo sapiens (Human)) | BDBM50365819
(CHEMBL1956998)Show SMILES CC(C)N1CCC[C@H](Cn2c(C)nc3cnc(Oc4ccc(F)cc4)cc3c2=O)C1 |r| Show InChI InChI=1S/C23H27FN4O2/c1-15(2)27-10-4-5-17(13-27)14-28-16(3)26-21-12-25-22(11-20(21)23(28)29)30-19-8-6-18(24)7-9-19/h6-9,11-12,15,17H,4-5,10,13-14H2,1-3H3/t17-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Prosidion Ltd
Curated by ChEMBL
| Assay Description
Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation counting |
Bioorg Med Chem Lett 22: 2271-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.078
BindingDB Entry DOI: 10.7270/Q20G3KMP |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50365819
(CHEMBL1956998)Show SMILES CC(C)N1CCC[C@H](Cn2c(C)nc3cnc(Oc4ccc(F)cc4)cc3c2=O)C1 |r| Show InChI InChI=1S/C23H27FN4O2/c1-15(2)27-10-4-5-17(13-27)14-28-16(3)26-21-12-25-22(11-20(21)23(28)29)30-19-8-6-18(24)7-9-19/h6-9,11-12,15,17H,4-5,10,13-14H2,1-3H3/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Prosidion Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human Erg by patch clamp assay |
Bioorg Med Chem Lett 22: 2271-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.078
BindingDB Entry DOI: 10.7270/Q20G3KMP |
More data for this
Ligand-Target Pair | |
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