BDBM50366000 CHEMBL1956437

SMILES: COc1cccc(CCC(=O)Nc2sc3CCCCc3c2C#N)c1

InChI Key: InChIKey=MOABVINOKVQLKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50366000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasoactive intestinal polypeptide receptor 1 (Rattus norvegicus)	BDBM50366000 (CHEMBL1956437) Show SMILES COc1cccc(CCC(=O)Nc2sc3CCCCc3c2C#N)c1 Show InChI InChI=1S/C19H20N2O2S/c1-23-14-6-4-5-13(11-14)9-10-18(22)21-19-16(12-20)15-7-2-3-8-17(15)24-19/h4-6,11H,2-3,7-10H2,1H3,(H,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Antagonist activity at vasoactive intestinal peptide receptor 1 in rat RKE cells assessed as inhibition of VIP-induced intracellular cAMP accumulatio...				Bioorg Med Chem Lett 22: 2287-90 (2012) Article DOI: 10.1016/j.bmcl.2012.01.082 BindingDB Entry DOI: 10.7270/Q2Q240QR
					More data for this Ligand-Target Pair