BDBM50366079 CHEMBL1956885

SMILES: Nc1nc(Nc2cccc(Br)c2)c2cc(Cc3ccc(Cl)cc3)[nH]c2n1

InChI Key: InChIKey=YHWUBFBUCSKQSU-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50366079   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50366079 (CHEMBL1956885) Show SMILES Nc1nc(Nc2cccc(Br)c2)c2cc(Cc3ccc(Cl)cc3)[nH]c2n1 Show InChI InChI=1S/C19H15BrClN5/c20-12-2-1-3-14(9-12)23-17-16-10-15(24-18(16)26-19(22)25-17)8-11-4-6-13(21)7-5-11/h1-7,9-10H,8H2,(H4,22,23,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of EGFR				Bioorg Med Chem 20: 2444-54 (2012) Article DOI: 10.1016/j.bmc.2012.01.029 BindingDB Entry DOI: 10.7270/Q2XK8G14
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50366079 (CHEMBL1956885) Show SMILES Nc1nc(Nc2cccc(Br)c2)c2cc(Cc3ccc(Cl)cc3)[nH]c2n1 Show InChI InChI=1S/C19H15BrClN5/c20-12-2-1-3-14(9-12)23-17-16-10-15(24-18(16)26-19(22)25-17)8-11-4-6-13(21)7-5-11/h1-7,9-10H,8H2,(H4,22,23,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta				Bioorg Med Chem 20: 2444-54 (2012) Article DOI: 10.1016/j.bmc.2012.01.029 BindingDB Entry DOI: 10.7270/Q2XK8G14
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50366079 (CHEMBL1956885) Show SMILES Nc1nc(Nc2cccc(Br)c2)c2cc(Cc3ccc(Cl)cc3)[nH]c2n1 Show InChI InChI=1S/C19H15BrClN5/c20-12-2-1-3-14(9-12)23-17-16-10-15(24-18(16)26-19(22)25-17)8-11-4-6-13(21)7-5-11/h1-7,9-10H,8H2,(H4,22,23,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem 20: 2444-54 (2012) Article DOI: 10.1016/j.bmc.2012.01.029 BindingDB Entry DOI: 10.7270/Q2XK8G14
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50366079 (CHEMBL1956885) Show SMILES Nc1nc(Nc2cccc(Br)c2)c2cc(Cc3ccc(Cl)cc3)[nH]c2n1 Show InChI InChI=1S/C19H15BrClN5/c20-12-2-1-3-14(9-12)23-17-16-10-15(24-18(16)26-19(22)25-17)8-11-4-6-13(21)7-5-11/h1-7,9-10H,8H2,(H4,22,23,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of VEGFR1				Bioorg Med Chem 20: 2444-54 (2012) Article DOI: 10.1016/j.bmc.2012.01.029 BindingDB Entry DOI: 10.7270/Q2XK8G14
					More data for this Ligand-Target Pair