null

SMILES: C=CCOc1ccc2ccc(=S)oc2c1

InChI Key: InChIKey=JKHHDRMDQLMVSB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50366106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50366106 (CHEMBL1957182) Show SMILES C=CCOc1ccc2ccc(=S)oc2c1 Show InChI InChI=1S/C12H10O2S/c1-2-7-13-10-5-3-9-4-6-12(15)14-11(9)8-10/h2-6,8H,1,7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 catalytic domain by Stopped-Flow CO2 Hydrase assay				J Med Chem 59: 462-73 (2016) BindingDB Entry DOI: 10.7270/Q2P2710K
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50366106 (CHEMBL1957182) Show SMILES C=CCOc1ccc2ccc(=S)oc2c1 Show InChI InChI=1S/C12H10O2S/c1-2-7-13-10-5-3-9-4-6-12(15)14-11(9)8-10/h2-6,8H,1,7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 after 6 hrs by stop-flow CO2 hydration assay				Bioorg Med Chem 20: 2266-73 (2012) Article DOI: 10.1016/j.bmc.2012.02.014 BindingDB Entry DOI: 10.7270/Q2P26ZK0
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50366106 (CHEMBL1957182) Show SMILES C=CCOc1ccc2ccc(=S)oc2c1 Show InChI InChI=1S/C12H10O2S/c1-2-7-13-10-5-3-9-4-6-12(15)14-11(9)8-10/h2-6,8H,1,7H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 catalytic domain by Stopped-Flow CO2 Hydrase assay				J Med Chem 59: 462-73 (2016) BindingDB Entry DOI: 10.7270/Q2P2710K
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50366106 (CHEMBL1957182) Show SMILES C=CCOc1ccc2ccc(=S)oc2c1 Show InChI InChI=1S/C12H10O2S/c1-2-7-13-10-5-3-9-4-6-12(15)14-11(9)8-10/h2-6,8H,1,7H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 after 6 hrs by stop-flow CO2 hydration assay				Bioorg Med Chem 20: 2266-73 (2012) Article DOI: 10.1016/j.bmc.2012.02.014 BindingDB Entry DOI: 10.7270/Q2P26ZK0
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50366106 (CHEMBL1957182) Show SMILES C=CCOc1ccc2ccc(=S)oc2c1 Show InChI InChI=1S/C12H10O2S/c1-2-7-13-10-5-3-9-4-6-12(15)14-11(9)8-10/h2-6,8H,1,7H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 by Stopped-Flow CO2 Hydrase assay				J Med Chem 59: 462-73 (2016) BindingDB Entry DOI: 10.7270/Q2P2710K
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50366106 (CHEMBL1957182) Show SMILES C=CCOc1ccc2ccc(=S)oc2c1 Show InChI InChI=1S/C12H10O2S/c1-2-7-13-10-5-3-9-4-6-12(15)14-11(9)8-10/h2-6,8H,1,7H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 after 6 hrs by stop-flow CO2 hydration assay				Bioorg Med Chem 20: 2266-73 (2012) Article DOI: 10.1016/j.bmc.2012.02.014 BindingDB Entry DOI: 10.7270/Q2P26ZK0
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50366106 (CHEMBL1957182) Show SMILES C=CCOc1ccc2ccc(=S)oc2c1 Show InChI InChI=1S/C12H10O2S/c1-2-7-13-10-5-3-9-4-6-12(15)14-11(9)8-10/h2-6,8H,1,7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 by Stopped-Flow CO2 Hydrase assay				J Med Chem 59: 462-73 (2016) BindingDB Entry DOI: 10.7270/Q2P2710K
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50366106 (CHEMBL1957182) Show SMILES C=CCOc1ccc2ccc(=S)oc2c1 Show InChI InChI=1S/C12H10O2S/c1-2-7-13-10-5-3-9-4-6-12(15)14-11(9)8-10/h2-6,8H,1,7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 after 6 hrs by stop-flow CO2 hydration assay				Bioorg Med Chem 20: 2266-73 (2012) Article DOI: 10.1016/j.bmc.2012.02.014 BindingDB Entry DOI: 10.7270/Q2P26ZK0
					More data for this Ligand-Target Pair