BDBM50366135 CHEMBL1957302
SMILES: COc1ccc2c(c[nH]c2c1)-c1nc2ccccc2cc1C#N
InChI Key: InChIKey=YDWHKZUXXIWDPQ-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50366135 (CHEMBL1957302) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 890 | n/a | n/a | n/a | n/a |
University of Hyderabad Campus Curated by ChEMBL | Assay Description Inhibition of PDE4B expressed in HEK293 cells assessed as fold reduction in forskolin-stimulated cAMP production pretreated for 30 mins measured 4 hr... | Bioorg Med Chem 20: 2199-207 (2012) Article DOI: 10.1016/j.bmc.2012.02.027 BindingDB Entry DOI: 10.7270/Q28S4QDM | |||||||||||
More data for this Ligand-Target Pair |