BDBM50366241 CHEMBL297624::L-652731
SMILES: COc1cc(cc(OC)c1OC)[C@H]1CC[C@@H](O1)c1cc(OC)c(OC)c(OC)c1
InChI Key: InChIKey=YCCPYTPBHUIHGW-HZPDHXFCSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Platelet activating factor receptor (Cavia porcellus) | BDBM50366241 (CHEMBL297624 | L-652731) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 103 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration required to inhibit PAF binding to rabbit platelet membrane | Bioorg Med Chem Lett 1: 327-332 (1991) Article DOI: 10.1016/S0960-894X(01)80818-0 BindingDB Entry DOI: 10.7270/Q2TM7BKP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet activating factor receptor (Homo sapiens (Human)) | BDBM50366241 (CHEMBL297624 | L-652731) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 103 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of the binding of [3H]C18-Platelet activating factor to human platelet membrane preparation | J Med Chem 35: 3474-82 (1992) BindingDB Entry DOI: 10.7270/Q2445N3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet activating factor receptor (Cavia porcellus) | BDBM50366241 (CHEMBL297624 | L-652731) | MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Sankyo Co. Ltd Curated by ChEMBL | Assay Description Inhibiting Platelet activating factor receptor by radioreceptor binding assay using rabbit platelets and [3H]-PAF | J Med Chem 39: 5281-4 (1997) Article DOI: 10.1021/jm950640q BindingDB Entry DOI: 10.7270/Q2FF3T06 | |||||||||||
More data for this Ligand-Target Pair |