BindingDB PrimarySearch

BDBM50366567 ATOMOXETINE

SMILES: CNCC[C@@H](Oc1ccccc1C)c1ccccc1

InChI Key: InChIKey=VHGCDTVCOLNTBX-QGZVFWFLSA-N

Data: 9 KI 31 IC50 3 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 43 hits for monomerid = 50366567
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hong Kong University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of [3H]- NE reuptake into rat hippocampal synaptosomes				Bioorg Med Chem Lett 8: 487-92 (1999) BindingDB Entry DOI: 10.7270/Q2F76D26
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus (rat))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The State University of New York Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometry				Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95
The State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to inhibit reuptake of norepinephrine ([3H]NE) at norepinephrine transporter of rat parietal/occipital region				Bioorg Med Chem Lett 13: 3565-9 (2003) BindingDB Entry DOI: 10.7270/Q26110WV
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hong Kong University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT reuptake into rat frontal cortex synaptosomes				Bioorg Med Chem Lett 8: 487-92 (1999) BindingDB Entry DOI: 10.7270/Q2F76D26
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to inhibit reuptake of serotonin ([3H]5-HT) at serotonin transporter of rat midbrian				Bioorg Med Chem Lett 13: 3565-9 (2003) BindingDB Entry DOI: 10.7270/Q26110WV
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	708	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligand				J Med Chem 43: 4151-9 (2000) Article DOI: 10.1021/jm990472s BindingDB Entry DOI: 10.7270/Q2PK0JWZ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hong Kong University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of [3H]- DA reuptake into rat striatal synaptosomes				Bioorg Med Chem Lett 8: 487-92 (1999) BindingDB Entry DOI: 10.7270/Q2F76D26
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Ability to inhibit reuptake of dopamine ([3H]DA) at dopamine transporter of rat striatum				Bioorg Med Chem Lett 13: 3565-9 (2003) BindingDB Entry DOI: 10.7270/Q26110WV
Georgetown University Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The State University of New York Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometry				Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95
The State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT expressed in JAR cels				Bioorg Med Chem Lett 18: 6067-70 (2008) Article DOI: 10.1016/j.bmcl.2008.10.026 BindingDB Entry DOI: 10.7270/Q2JD4XQT
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Bioscience, Inc. Curated by ChEMBL					Assay Description Inhibition of human DAT				Bioorg Med Chem Lett 18: 1346-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.011 BindingDB Entry DOI: 10.7270/Q2S183BV
Neurocrine Bioscience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The State University of New York Curated by ChEMBL					Assay Description Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometry				Bioorg Med Chem Lett 19: 58-61 (2008) Article DOI: 10.1016/j.bmcl.2008.11.022 BindingDB Entry DOI: 10.7270/Q2N58N95
The State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in HEK293 cells by patch-clamp method				J Med Chem 51: 7265-72 (2009) Article DOI: 10.1021/jm8009537 BindingDB Entry DOI: 10.7270/Q2H41SCG
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [alpha,beta-3H(N)]-5-hydroxytryptamine from human cloned SERT expressed in HEK293 cells by microplate scintillation counter				J Med Chem 51: 7265-72 (2009) Article DOI: 10.1021/jm8009537 BindingDB Entry DOI: 10.7270/Q2H41SCG
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of 3,4-[ring-2,5,6-3H]dihydroxyphenylethylamine from human cloned DAT expressed in HEK293 cells by microplate scintillation counter				J Med Chem 51: 7265-72 (2009) Article DOI: 10.1021/jm8009537 BindingDB Entry DOI: 10.7270/Q2H41SCG
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Bioscience, Inc. Curated by ChEMBL					Assay Description Inhibition of human SERT				Bioorg Med Chem Lett 18: 1346-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.011 BindingDB Entry DOI: 10.7270/Q2S183BV
Neurocrine Bioscience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Bioscience, Inc. Curated by ChEMBL					Assay Description Inhibition of human NET				Bioorg Med Chem Lett 18: 1346-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.011 BindingDB Entry DOI: 10.7270/Q2S183BV
Neurocrine Bioscience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 20: 1555-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.056 BindingDB Entry DOI: 10.7270/Q2FN175Q
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4491-4 (2008) Article DOI: 10.1016/j.bmcl.2008.07.049 BindingDB Entry DOI: 10.7270/Q2S75H8V
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4491-4 (2008) Article DOI: 10.1016/j.bmcl.2008.07.049 BindingDB Entry DOI: 10.7270/Q2S75H8V
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of dopamine uptake at human DAT expressed in HEK293 cells				Bioorg Med Chem Lett 18: 4491-4 (2008) Article DOI: 10.1016/j.bmcl.2008.07.049 BindingDB Entry DOI: 10.7270/Q2S75H8V
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant CYP32D6				Bioorg Med Chem Lett 18: 4491-4 (2008) Article DOI: 10.1016/j.bmcl.2008.07.049 BindingDB Entry DOI: 10.7270/Q2S75H8V
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 19: 2464-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.054 BindingDB Entry DOI: 10.7270/Q2T43V1C
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT expressed in human JAR cells				Bioorg Med Chem Lett 19: 2464-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.054 BindingDB Entry DOI: 10.7270/Q2T43V1C
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
Neurocrine Biosciences Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
Neurocrine Biosciences Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Inhibition of dopamine uptake at human DAT in human HEK293 cells				Bioorg Med Chem Lett 18: 4224-7 (2008) Article DOI: 10.1016/j.bmcl.2008.05.057 BindingDB Entry DOI: 10.7270/Q2T154J4
Neurocrine Biosciences Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK cells				Bioorg Med Chem Lett 18: 4929-31 (2008) Article DOI: 10.1016/j.bmcl.2008.08.060 BindingDB Entry DOI: 10.7270/Q2S183C9
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of serotonin uptake at human SERT expressed in JAR cells				Bioorg Med Chem Lett 18: 4929-31 (2008) Article DOI: 10.1016/j.bmcl.2008.08.060 BindingDB Entry DOI: 10.7270/Q2S183C9
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 4 (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Canalicular multispecific organic anion transporter 1 (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Canalicular multispecific organic anion transporter 2 (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cells				Bioorg Med Chem Lett 18: 6067-70 (2008) Article DOI: 10.1016/j.bmcl.2008.10.026 BindingDB Entry DOI: 10.7270/Q2JD4XQT
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation counting				J Med Chem 52: 5703-11 (2009) Article DOI: 10.1021/jm900888c BindingDB Entry DOI: 10.7270/Q2CR5V9W
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Bioscience, Inc. Curated by ChEMBL					Assay Description Inhibition of human DAT				Bioorg Med Chem Lett 18: 3328-32 (2008) Article DOI: 10.1016/j.bmcl.2008.04.025 BindingDB Entry DOI: 10.7270/Q21V5FTK
Neurocrine Bioscience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Bioscience, Inc. Curated by ChEMBL					Assay Description Inhibition of human SERT				Bioorg Med Chem Lett 18: 3328-32 (2008) Article DOI: 10.1016/j.bmcl.2008.04.025 BindingDB Entry DOI: 10.7270/Q21V5FTK
Neurocrine Bioscience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Bioscience, Inc. Curated by ChEMBL					Assay Description Inhibition of human NET				Bioorg Med Chem Lett 18: 3328-32 (2008) Article DOI: 10.1016/j.bmcl.2008.04.025 BindingDB Entry DOI: 10.7270/Q21V5FTK
Neurocrine Bioscience, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank PubMed	n/a	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a
Hong Kong University of Science and Technology Curated by ChEMBL					Assay Description Equilibrium dissociation constant (KD) for Competitive binding between [3H]- imipramine and the compound at human transporter-hSERT				Bioorg Med Chem Lett 8: 487-92 (1999) BindingDB Entry DOI: 10.7270/Q2F76D26
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank PubMed	n/a	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a
Hong Kong University of Science and Technology Curated by ChEMBL					Assay Description Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT				Bioorg Med Chem Lett 8: 487-92 (1999) BindingDB Entry DOI: 10.7270/Q2F76D26
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank PubMed	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
Hong Kong University of Science and Technology Curated by ChEMBL					Assay Description Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporter				Bioorg Med Chem Lett 8: 487-92 (1999) BindingDB Entry DOI: 10.7270/Q2F76D26
					More data for this Ligand-Target Pair
Krueppel-like factor 10 (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Beth Israel Deaconess Medical Center Curated by ChEMBL					Assay Description Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d...				J Med Chem 58: 1466-78 (2015) Article DOI: 10.1021/jm5018187 BindingDB Entry DOI: 10.7270/Q2WM1G3D
Beth Israel Deaconess Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50366567 (ATOMOXETINE) Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of Levo[ring-2,5,6-3H]norepinephrine from human cloned NET expressed in HEK293 cells by microplate scintillation counter				J Med Chem 51: 7265-72 (2009) Article DOI: 10.1021/jm8009537 BindingDB Entry DOI: 10.7270/Q2H41SCG
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair