BDBM50366600 CHEMBL301281
SMILES: COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(=O)c1ccccc1)N2
InChI Key: InChIKey=AYDBLCSLKNTEJL-CLRIEMFWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50366600 (CHEMBL301281) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranes | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50366600 (CHEMBL301281) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgetown University Medical Center Curated by ChEMBL | Assay Description Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes) | Bioorg Med Chem Lett 9: 1831-6 (1999) BindingDB Entry DOI: 10.7270/Q2KS6S3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50366600 (CHEMBL301281) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [3H]WIN-35428 binding to the dopamine transporter in rat striata. | J Med Chem 39: 4027-35 (1996) Article DOI: 10.1021/jm960409s BindingDB Entry DOI: 10.7270/Q22B8ZNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50366600 (CHEMBL301281) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [3H]paroxetine binding to serotonin transporter in rat frontal cortex | J Med Chem 39: 4027-35 (1996) Article DOI: 10.1021/jm960409s BindingDB Entry DOI: 10.7270/Q22B8ZNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Norepinephrine Monoamine transporters (Rattus norvegicus) | BDBM50366600 (CHEMBL301281) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 139 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [3H]nisoxetine binding to the norepinephrine transporter in rat midbrain. | J Med Chem 39: 4027-35 (1996) Article DOI: 10.1021/jm960409s BindingDB Entry DOI: 10.7270/Q22B8ZNT | |||||||||||
More data for this Ligand-Target Pair |