BDBM50366915 CHEMBL1788220
SMILES: CN(C)CCNC(=O)C1=C[C@]2(CC1)CCN(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1)c1ccccc1C2
InChI Key: InChIKey=VTTUVOLMPNOBRT-LDLOPFEMSA-N
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50366915 (CHEMBL1788220) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Evaluated for accumulation of cAMP in transfected HEK293 cells expressing human vasopressin V2 receptor | Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50366915 (CHEMBL1788220) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Evaluated for intracellular calcium mobilization in HEK- 293 cells transfected to express human vasopressin V1a receptor (Compound 7o) | Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 Receptor (Rattus norvegicus (Rat)) | BDBM50366915 (CHEMBL1788220) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Evaluated for binding affinity towards vasopressin V2 receptor in rat | Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM50366915 (CHEMBL1788220) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Binding affinity measured by inhibition of 3[H] AVP binding to cloned human vasopressin V1a receptor | Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AVPR1A (RAT) | BDBM50366915 (CHEMBL1788220) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Evaluated for binding affinity towards vasopressin V1a receptor in rat | Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM50366915 (CHEMBL1788220) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Evaluated for intracellular calcium mobilization in HEK293 cells transfected to express human vasopressin V1a receptor | Bioorg Med Chem Lett 14: 3143-6 (2004) Article DOI: 10.1016/j.bmcl.2004.04.016 BindingDB Entry DOI: 10.7270/Q2Z60PMQ | |||||||||||
More data for this Ligand-Target Pair |