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BDBM50367272 CHEMBL605460

SMILES: Cc1ccccc1NC(=O)Cc1ccc(Nc2ncnc3n(cnc23)C2O[C@H](CO)[C@@H](O)[C@H]2O)cc1

InChI Key: InChIKey=GSNAEQKSRSPWCT-PMJLDSSESA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50367272   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosine receptor A1


(Rattus norvegicus (rat))		BDBM50367272
PNG
(CHEMBL605460)
Show SMILES Cc1ccccc1NC(=O)Cc1ccc(Nc2ncnc3n(cnc23)C2O[C@H](CO)[C@@H](O)[C@H]2O)cc1 |r|
Show InChI InChI=1S/C25H26N6O5/c1-14-4-2-3-5-17(14)30-19(33)10-15-6-8-16(9-7-15)29-23-20-24(27-12-26-23)31(13-28-20)25-22(35)21(34)18(11-32)36-25/h2-9,12-13,18,21-22,25,32,34-35H,10-11H2,1H3,(H,30,33)(H,26,27,29)/t18-,21-,22-,25?/m1/s1
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PC cid
PC sid
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Similars
PubMed
 6.80n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of binding of 1 nM N6-[3H]cyclohexyladenosine to adenosine A1 receptor on rat cerebral cortical membranes.

J Med Chem 28: 1341-6 (1985)


BindingDB Entry DOI: 10.7270/Q2BP03CS
More data for this
Ligand-Target Pair