BDBM50367331 CHEMBL1791417
SMILES: NC(CCS(=O)C(CP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O
InChI Key: InChIKey=MXSOOYSYSMMHNI-JLJGMEGWSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-adenosylmethionine synthetase (MAT 1 and MAT 2) (Rattus norvegicus) | BDBM50367331 (CHEMBL1791417) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 8.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant was evaluated on novikoff hepatoma (MAT-T) form of rat methionine adenosyltransferase, when ATP was the variable substrate (60 uM... | J Med Chem 29: 1030-8 (1986) BindingDB Entry DOI: 10.7270/Q2CF9QN4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine synthetase (MAT 1 and MAT 2) (Rattus norvegicus) | BDBM50367331 (CHEMBL1791417) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable... | J Med Chem 29: 1030-8 (1986) BindingDB Entry DOI: 10.7270/Q2CF9QN4 | |||||||||||
More data for this Ligand-Target Pair |