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BDBM50367425 CHEMBL1743955

SMILES: Fc1ccc(cc1)C(CCCN1CCc2[nH]c3ccc(F)cc3c2C1)c1ccc(F)cc1

InChI Key: InChIKey=FDZCICPSBGWJFW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50367425   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50367425
PNG
(CHEMBL1743955)
Show SMILES Fc1ccc(cc1)C(CCCN1CCc2[nH]c3ccc(F)cc3c2C1)c1ccc(F)cc1
Show InChI InChI=1S/C27H25F3N2/c28-20-7-3-18(4-8-20)23(19-5-9-21(29)10-6-19)2-1-14-32-15-13-27-25(17-32)24-16-22(30)11-12-26(24)31-27/h3-12,16,23,31H,1-2,13-15,17H2
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PubMed
 18n/an/an/an/an/an/an/an/a



Wyeth Laboratories

Curated by ChEMBL


Assay Description
In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound ; value may r...

J Med Chem 30: 1818-23 (1987)


BindingDB Entry DOI: 10.7270/Q2NS0VG2
More data for this
Ligand-Target Pair