BDBM50367587 CHEMBL1743793

SMILES: Oc1cccc(c1)[C@@H]1CN2CCC[C@@H]2c2ccccc12

InChI Key: InChIKey=ZJKFQBZJTWPEIQ-ZWKOTPCHSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50367587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50367587 (CHEMBL1743793) Show SMILES Oc1cccc(c1)[C@@H]1CN2CCC[C@@H]2c2ccccc12 |r| Show InChI InChI=1S/C18H19NO/c20-14-6-3-5-13(11-14)17-12-19-10-4-9-18(19)16-8-2-1-7-15(16)17/h1-3,5-8,11,17-18,20H,4,9-10,12H2/t17-,18+/m0/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of uptake of tritiated norepinephrine (NE) in rat synaptosomes				J Med Chem 30: 1433-54 (1987) BindingDB Entry DOI: 10.7270/Q2D50NJ3
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50367587 (CHEMBL1743793) Show SMILES Oc1cccc(c1)[C@@H]1CN2CCC[C@@H]2c2ccccc12 |r| Show InChI InChI=1S/C18H19NO/c20-14-6-3-5-13(11-14)17-12-19-10-4-9-18(19)16-8-2-1-7-15(16)17/h1-3,5-8,11,17-18,20H,4,9-10,12H2/t17-,18+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of the uptake of tritiated dopamine (DA) in rat synaptosomes				J Med Chem 30: 1433-54 (1987) BindingDB Entry DOI: 10.7270/Q2D50NJ3
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50367587 (CHEMBL1743793) Show SMILES Oc1cccc(c1)[C@@H]1CN2CCC[C@@H]2c2ccccc12 |r| Show InChI InChI=1S/C18H19NO/c20-14-6-3-5-13(11-14)17-12-19-10-4-9-18(19)16-8-2-1-7-15(16)17/h1-3,5-8,11,17-18,20H,4,9-10,12H2/t17-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition the uptake of tritiated serotonin (5-HT) by the serotonin transporter SERT in rat synaptosomes				J Med Chem 30: 1433-54 (1987) BindingDB Entry DOI: 10.7270/Q2D50NJ3
					More data for this Ligand-Target Pair