BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM50368315 PROSTRATIN

SMILES: C[C@@H]1C[C@]2(OC(C)=O)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]13O)C2(C)C

InChI Key: InChIKey=BOJKFRKNLSCGHY-KUHYLXMHSA-N

Data: 3 KI 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50368315
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein Kinase C, alpha (Bos taurus (bovine))	BDBM50368315 (PROSTRATIN) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserine				J Med Chem 44: 1892-904 (2001) BindingDB Entry DOI: 10.7270/Q2H995WH
National Cancer Institute at Frederick Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, PKC; classical/novel (Homo sapiens (Human))	BDBM50368315 (PROSTRATIN) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute (NCI) Curated by ChEMBL					Assay Description Displacement of [3H]PDBu binding to Protein kinase C of CEM cells with 10% fetal calf serum				J Med Chem 35: 1978-86 (1992) BindingDB Entry DOI: 10.7270/Q22Z17SG
National Cancer Institute (NCI) Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C, PKC; classical/novel (Homo sapiens (Human))	BDBM50368315 (PROSTRATIN) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute (NCI) Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from Protein kinase C of CEM cells				J Med Chem 35: 1978-86 (1992) BindingDB Entry DOI: 10.7270/Q22Z17SG
National Cancer Institute (NCI) Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C (PKC) (Homo sapiens (Human))	BDBM50368315 (PROSTRATIN) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	910	n/a	n/a	n/a	n/a
Kaohsiung Medical University Curated by ChEMBL					Assay Description Activation of PKC in human platelet assessed as induction of platelet aggregation measured within 15 mins by tribidimetric method				J Nat Prod 79: 2658-2666 (2016) Article DOI: 10.1021/acs.jnatprod.6b00603 BindingDB Entry DOI: 10.7270/Q24T6N3M
Kaohsiung Medical University Curated by ChEMBL					More data for this Ligand-Target Pair