BDBM50368723 Metanopirone::Sediel::TANDOSPIRONE HYDROCHLORIDE::Tandospirone
SMILES: O=C1[C@H]2[C@@H]3CC[C@@H](C3)[C@H]2C(=O)N1CCCCN1CCN(CC1)c1ncccn1
InChI Key: InChIKey=CEIJFEGBUDEYSX-FZDBZEDMSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50368723 (Metanopirone | Sediel | TANDOSPIRONE HYDROCHLORIDE...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | 0.00270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Chemical Industry Company, Ltd. Curated by ChEMBL | Assay Description Binding affinity by measuring displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampus | J Med Chem 36: 3526-32 (1994) BindingDB Entry DOI: 10.7270/Q2D21Z74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50368723 (Metanopirone | Sediel | TANDOSPIRONE HYDROCHLORIDE...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Asahi Chemical Industry Company, Ltd. Curated by ChEMBL | Assay Description Binding affinity for DA2 receptor | J Med Chem 36: 3526-32 (1994) BindingDB Entry DOI: 10.7270/Q2D21Z74 | |||||||||||
More data for this Ligand-Target Pair |