BDBM50369261 CHEMBL1907812

SMILES: C[C@H](CN(O)C(N)=O)C#Cc1ccc(Oc2ccc(F)cc2)o1

InChI Key: InChIKey=DLTQPPWEZZJXHC-NSHDSACASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50369261 (CHEMBL1907812) Show SMILES C[C@H](CN(O)C(N)=O)C#Cc1ccc(Oc2ccc(F)cc2)o1 |r| Show InChI InChI=1S/C16H15FN2O4/c1-11(10-19(21)16(18)20)2-5-13-8-9-15(22-13)23-14-6-3-12(17)4-7-14/h3-4,6-9,11,21H,10H2,1H3,(H2,18,20)/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase (5-LO) measured as LTB4 production in human whole blood stimulated with calcium ionophore (A23187).				J Med Chem 40: 1955-68 (1997) Article DOI: 10.1021/jm9700474 BindingDB Entry DOI: 10.7270/Q2NV9JWT
					More data for this Ligand-Target Pair