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SMILES: Nc1ncnc2n(cnc12)C1O[C@H](C#CI)[C@@H](O)[C@H]1O

InChI Key: InChIKey=SLDOTDVQNFUCHQ-YNJARDAQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369393   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosylhomocysteinase


(Homo sapiens (Human))		BDBM50369393
PNG
(CHEMBL608312)
Show SMILES Nc1ncnc2n(cnc12)C1O[C@H](C#CI)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C11H10IN5O3/c12-2-1-5-7(18)8(19)11(20-5)17-4-16-6-9(13)14-3-15-10(6)17/h3-5,7-8,11,18-19H,(H2,13,14,15)/t5-,7-,8-,11?/m1/s1
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Article
PubMed
 1.10E+3n/an/an/an/an/an/an/an/a



Brigham Young University

Curated by ChEMBL


Assay Description
Kinetic constant calculated from the pseudo-first-order rate constant(k app) for S-adenosyl-homocysteine hydrolase inactivation

J Med Chem 41: 3857-64 (1998)


Article DOI: 10.1021/jm980163m
BindingDB Entry DOI: 10.7270/Q2DR2W64
More data for this
Ligand-Target Pair