BDBM50369543 CHEMBL610370

SMILES: Cn1nc(NC(=O)C(C)(C)C)c2cn(C3O[C@H](CO)[C@@H](O)[C@H]3O)c3ncnc1c23

InChI Key: InChIKey=KZSLKSHWYOKPFQ-JZVWYZPUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50369543 (CHEMBL610370) Show SMILES Cn1nc(NC(=O)C(C)(C)C)c2cn(C3O[C@H](CO)[C@@H](O)[C@H]3O)c3ncnc1c23 |r| Show InChI InChI=1S/C18H24N6O5/c1-18(2,3)17(28)21-13-8-5-24(16-12(27)11(26)9(6-25)29-16)15-10(8)14(19-7-20-15)23(4)22-13/h5,7,9,11-12,16,25-27H,6H2,1-4H3,(H,21,22,28)/t9-,11-,12-,16?/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Antiviral activity was evaluated by RT (reverse transcriptase) activity in cells acutely infected with HIV-1				J Med Chem 43: 2457-63 (2000) BindingDB Entry DOI: 10.7270/Q22N52Z2
					More data for this Ligand-Target Pair