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SMILES: C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cccc(c2)[N+]([O-])=O)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2

InChI Key: InChIKey=GVHDARWHDKAEGH-LWQDQPMZSA-O

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369960   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))		BDBM50369960
PNG
(CHEMBL1204019)
Show SMILES C[n+]1ccc(cc1)-c1c2ccc(n2)c(-c2cc[n+](C)cc2)c2ccc([nH]2)c(-c2cccc(c2)[N+]([O-])=O)c2ccc([nH]2)c(-c2cc[n+](C)cc2)c2ccc1n2
Show InChI InChI=1S/C44H34N8O2/c1-49-21-15-28(16-22-49)41-33-7-9-35(45-33)42(29-17-23-50(2)24-18-29)37-11-13-39(47-37)44(31-5-4-6-32(27-31)52(53)54)40-14-12-38(48-40)43(36-10-8-34(41)46-36)30-19-25-51(3)26-20-30/h4-27H,1-3H3,(H,45,46,47,48)/q+2/p+1/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-
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Similars
PubMed
n/an/a 1.20E+4n/an/an/an/an/an/a



University of Texas at Austin

Curated by ChEMBL


Assay Description
Apparent telomerase inhibition by G-quadruplex mechanism

J Med Chem 44: 4509-23 (2001)


BindingDB Entry DOI: 10.7270/Q25Q4WVW
More data for this
Ligand-Target Pair