BDBM50370222 CHEMBL610866

SMILES: Nc1ncnc2n(C3O[C@H](COP(O)(=O)OC4[C@H](O)[C@@H](COP(O)(=O)O[C@@H]5[C@H](O)[C@@H](COP(O)(=O)O[C@@H]6[C@H](O)[C@@H](CO)OC6n6c(N=[N+]=[N-])nc7c(N)ncnc67)OC5n5c(N=[N+]=[N-])nc6c(N)ncnc56)OC4n4c(N=[N+]=[N-])nc5c(N)ncnc45)[C@@H](O)[C@H]3O)c(N=[N+]=[N-])nc12

InChI Key: InChIKey=MECYXKPTPRZDEK-KFGXQIDSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNase L (Mus musculus)	BDBM50370222 (CHEMBL610866) Show SMILES Nc1ncnc2n(C3O[C@H](COP(O)(=O)OC4[C@H](O)[C@@H](COP(O)(=O)O[C@@H]5[C@H](O)[C@@H](COP(O)(=O)O[C@@H]6[C@H](O)[C@@H](CO)OC6n6c(N=[N+]=[N-])nc7c(N)ncnc67)OC5n5c(N=[N+]=[N-])nc6c(N)ncnc56)OC4n4c(N=[N+]=[N-])nc5c(N)ncnc45)[C@@H](O)[C@H]3O)c(N=[N+]=[N-])nc12 |r| Show InChI InChI=1S/C40H45N32O22P3/c41-25-13-29(53-5-49-25)69(37(57-13)61-65-45)33-21(78)17(74)10(89-33)2-85-95(79,80)93-23-19(76)12(91-35(23)71-31-15(27(43)51-7-55-31)59-39(71)63-67-47)4-87-97(83,84)94-24-20(77)11(90-36(24)72-32-16(28(44)52-8-56-32)60-40(72)64-68-48)3-86-96(81,82)92-22-18(75)9(1-73)88-34(22)70-30-14(26(42)50-6-54-30)58-38(70)62-66-46/h5-12,17-24,33-36,73-78H,1-4H2,(H,79,80)(H,81,82)(H,83,84)(H2,41,49,53)(H2,42,50,54)(H2,43,51,55)(H2,44,52,56)/t9-,10-,11-,12-,17-,18-,19-,20-,21-,22-,23?,24-,33?,34?,35?,36?/m1/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Gunma University Curated by ChEMBL					Assay Description Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liver				J Med Chem 46: 4926-32 (2003) Article DOI: 10.1021/jm030035k BindingDB Entry DOI: 10.7270/Q2QR4XVM
					More data for this Ligand-Target Pair