BDBM50370225 CHEMBL608161

SMILES: Nc1nc2c(N)ncnc2n1C1O[C@H](COP(O)(=O)O[C@@H]2[C@H](O)[C@@H](COP(O)(O)=O)OC2n2c(N)nc3c(N)ncnc23)[C@@H](O)[C@H]1O

InChI Key: InChIKey=KUDFESJEASMDIF-IXVYOMHZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNase L (Mus musculus)	BDBM50370225 (CHEMBL608161) Show SMILES Nc1nc2c(N)ncnc2n1C1O[C@H](COP(O)(=O)O[C@@H]2[C@H](O)[C@@H](COP(O)(O)=O)OC2n2c(N)nc3c(N)ncnc23)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C20H28N12O13P2/c21-13-7-15(27-3-25-13)31(19(23)29-7)17-11(35)9(33)5(43-17)2-42-47(39,40)45-12-10(34)6(1-41-46(36,37)38)44-18(12)32-16-8(30-20(32)24)14(22)26-4-28-16/h3-6,9-12,17-18,33-35H,1-2H2,(H2,23,29)(H2,24,30)(H,39,40)(H2,21,25,27)(H2,22,26,28)(H2,36,37,38)/t5-,6-,9-,10-,11-,12-,17?,18?/m1/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gunma University Curated by ChEMBL					Assay Description Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liver				J Med Chem 46: 4926-32 (2003) Article DOI: 10.1021/jm030035k BindingDB Entry DOI: 10.7270/Q2QR4XVM
					More data for this Ligand-Target Pair