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BDBM50370226 CHEMBL607595

SMILES: Nc1nc2c(N)ncnc2n1C1O[C@H](COP(P)(=O)O[C@@H]2[C@H](O)[C@@H](COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](CO)OC3n3c(N)nc4c(N)ncnc34)OC2n2c(N)nc3c(N)ncnc23)[C@@H](O)[C@H]1O

InChI Key: InChIKey=IAASHHFOGCSFFX-QHJDRJCFSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370226   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNase L


(Mus musculus)		BDBM50370226
PNG
(CHEMBL607595)
Show SMILES Nc1nc2c(N)ncnc2n1C1O[C@H](COP(P)(=O)O[C@@H]2[C@H](O)[C@@H](COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](CO)OC3n3c(N)nc4c(N)ncnc34)OC2n2c(N)nc3c(N)ncnc23)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C30H41N18O15P3/c31-19-10-22(40-4-37-19)46(28(34)43-10)25-16(53)13(50)8(60-25)3-58-66(56,64)63-18-15(52)9(61-27(18)48-24-12(45-30(48)36)21(33)39-6-42-24)2-57-65(54,55)62-17-14(51)7(1-49)59-26(17)47-23-11(44-29(47)35)20(32)38-5-41-23/h4-9,13-18,25-27,49-53H,1-3,64H2,(H2,34,43)(H2,35,44)(H2,36,45)(H,54,55)(H2,31,37,40)(H2,32,38,41)(H2,33,39,42)/t7-,8-,9-,13-,14-,15-,16-,17-,18-,25?,26?,27?,66?/m1/s1
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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UniChem

Similars
Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



Gunma University

Curated by ChEMBL


Assay Description
Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liver

J Med Chem 46: 4926-32 (2003)


Article DOI: 10.1021/jm030035k
BindingDB Entry DOI: 10.7270/Q2QR4XVM
More data for this
Ligand-Target Pair