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BDBM50370229 CHEMBL607600

SMILES: Nc1ncnc2n(C3O[C@H](COP(O)(=O)O[C@@H]4[C@H](O)[C@@H](COP(O)(O)=O)OC4n4c(N=[N+]=[N-])nc5c(N)ncnc45)[C@@H](O)[C@H]3O)c(N=[N+]=[N-])nc12

InChI Key: InChIKey=KLKBALXUIOMALU-IXVYOMHZSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370229   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNase L


(Mus musculus)		BDBM50370229
PNG
(CHEMBL607600)
Show SMILES Nc1ncnc2n(C3O[C@H](COP(O)(=O)O[C@@H]4[C@H](O)[C@@H](COP(O)(O)=O)OC4n4c(N=[N+]=[N-])nc5c(N)ncnc45)[C@@H](O)[C@H]3O)c(N=[N+]=[N-])nc12 |r|
Show InChI InChI=1S/C20H24N16O13P2/c21-13-7-15(27-3-25-13)35(19(29-7)31-33-23)17-11(39)9(37)5(47-17)2-46-51(43,44)49-12-10(38)6(1-45-50(40,41)42)48-18(12)36-16-8(14(22)26-4-28-16)30-20(36)32-34-24/h3-6,9-12,17-18,37-39H,1-2H2,(H,43,44)(H2,21,25,27)(H2,22,26,28)(H2,40,41,42)/t5-,6-,9-,10-,11-,12-,17?,18?/m1/s1
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
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UniChem

Similars
Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Gunma University

Curated by ChEMBL


Assay Description
Displacement of [125I]-labeled 2-5A from 2-5A dependent Ribonuclease L (RNase L) of mouse liver

J Med Chem 46: 4926-32 (2003)


Article DOI: 10.1021/jm030035k
BindingDB Entry DOI: 10.7270/Q2QR4XVM
More data for this
Ligand-Target Pair