BDBM50370486 CHEMBL611097

SMILES: CN(C)c1nc2n(ccc2c(=O)[nH]1)C1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key: InChIKey=SNSRRFGLXRUTCB-RNRLFLAJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (eIF4E) (Homo sapiens (Human))	BDBM50370486 (CHEMBL611097) Show SMILES CN(C)c1nc2n(ccc2c(=O)[nH]1)C1O[C@H](CO)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C13H18N4O5/c1-16(2)13-14-10-6(11(21)15-13)3-4-17(10)12-9(20)8(19)7(5-18)22-12/h3-4,7-9,12,18-20H,5H2,1-2H3,(H,14,15,21)/t7-,8-,9-,12?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration against 7-methyl-GTP binding to eukaryotic translation initiation factor 4E				Bioorg Med Chem Lett 15: 2177-80 (2005) Article DOI: 10.1016/j.bmcl.2005.01.080 BindingDB Entry DOI: 10.7270/Q27D2VWP
					More data for this Ligand-Target Pair