BDBM50370492 CHEMBL607905

SMILES: Nc1nc2n(c[n+](CC=C)c2c(=O)[nH]1)C1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]1O

InChI Key: InChIKey=VDGFGJFPNNGZEH-PUXKXDTASA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (eIF4E) (Homo sapiens (Human))	BDBM50370492 (CHEMBL607905) Show SMILES Nc1nc2n(c[n+](CC=C)c2c(=O)[nH]1)C1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C13H18N5O8P/c1-2-3-17-5-18(10-7(17)11(21)16-13(14)15-10)12-9(20)8(19)6(26-12)4-25-27(22,23)24/h2,5-6,8-9,12,19-20H,1,3-4H2,(H4-,14,15,16,21,22,23,24)/p-1/t6-,8-,9-,12?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration against 7-methyl-GTP binding to eukaryotic translation initiation factor 4E				Bioorg Med Chem Lett 15: 2177-80 (2005) Article DOI: 10.1016/j.bmcl.2005.01.080 BindingDB Entry DOI: 10.7270/Q27D2VWP
					More data for this Ligand-Target Pair