BDBM50370548 NOGALAMYCIN
SMILES: CO[C@H]1[C@H](C)O[C@@H](O[C@H]2C[C@](C)(O)[C@H](C(=O)OC)c3cc4C(=O)c5c6O[C@@H]7O[C@@](C)([C@H](O)[C@H]([C@@H]7O)N(C)C)c6cc(O)c5C(=O)c4c(O)c23)[C@H](OC)[C@]1(C)OC
InChI Key: InChIKey=KGTDRFCXGRULNK-JYOBTZKQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA helicase [35-727] (Plasmodium falciparum) | BDBM50370548 (NOGALAMYCIN) | GoogleScholar AffyNet | Purchase KEGG MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
International Centre for Genetic Engineering and Biotechnology | Assay Description The hydrolysis of ATP catalyzed by PfUDN was assayed by measuring the formation of Pi from [γ-32P] ATP. The reaction mixture of 10 μl conta... | BMC Biochem 15: 9 (2014) Article DOI: 10.1186/1471-2091-15-9 BindingDB Entry DOI: 10.7270/Q25H7F45 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus) | BDBM50370548 (NOGALAMYCIN) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase KEGG MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wollongong Curated by ChEMBL | Assay Description Inhibitory concentration against hepatitis C virus helicase | J Med Chem 48: 1-20 (2005) Article DOI: 10.1021/jm0400101 BindingDB Entry DOI: 10.7270/Q2XP75Q1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA helicase [35-727] (Plasmodium falciparum) | BDBM50370548 (NOGALAMYCIN) | GoogleScholar AffyNet | Purchase KEGG MMDB PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
International Centre for Genetic Engineering and Biotechnology | Assay Description Helicase assay was demonstrated using the purified fraction of PfUDN. The specially designed partial duplex substrate consisted of a 32P-labelled 47-... | BMC Biochem 15: 9 (2014) Article DOI: 10.1186/1471-2091-15-9 BindingDB Entry DOI: 10.7270/Q25H7F45 | |||||||||||
More data for this Ligand-Target Pair |