BDBM50370584 Beepen-VK::Betapen-VK::PENICILLIN V::Penapar-VK::Penicillin Phenoxymethyl
SMILES: CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(O)=O
InChI Key: InChIKey=BPLBGHOLXOTWMN-MBNYWOFBSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Penicillin-binding protein 4 (Bacillus subtilis (strain 168)) | BDBM50370584 (Beepen-VK | Betapen-VK | PENICILLIN V | Penapar-VK...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wesleyan University Curated by ChEMBL | Assay Description Inhibition of Bacillus subtilis 168 PBP4 after 30 mins by SDS-PAGE | ACS Med Chem Lett 5: 154-7 (2014) Article DOI: 10.1021/ml400408c BindingDB Entry DOI: 10.7270/Q2NP27DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Penicillin-binding protein 3 (Bacillus subtilis (strain 168)) | BDBM50370584 (Beepen-VK | Betapen-VK | PENICILLIN V | Penapar-VK...) | MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wesleyan University Curated by ChEMBL | Assay Description Inhibition of Bacillus subtilis 168 PBP3 after 30 mins by SDS-PAGE | ACS Med Chem Lett 5: 154-7 (2014) Article DOI: 10.1021/ml400408c BindingDB Entry DOI: 10.7270/Q2NP27DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-alanyl-D-alanine carboxypeptidase DacA (Bacillus subtilis (strain 168)) | BDBM50370584 (Beepen-VK | Betapen-VK | PENICILLIN V | Penapar-VK...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wesleyan University Curated by ChEMBL | Assay Description Inhibition of Bacillus subtilis 168 PBP5 after 30 mins by SDS-PAGE | ACS Med Chem Lett 5: 154-7 (2014) Article DOI: 10.1021/ml400408c BindingDB Entry DOI: 10.7270/Q2NP27DF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligopeptide transporter small intestine isoform (Homo sapiens (Human)) | BDBM50370584 (Beepen-VK | Betapen-VK | PENICILLIN V | Penapar-VK...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | DrugBank Article PubMed | 2.10E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL | Assay Description Binding affinity against membrane transport protein PEPT1 in human Caco-2 cells | J Med Chem 48: 4410-9 (2005) Article DOI: 10.1021/jm048982w BindingDB Entry DOI: 10.7270/Q2Q24116 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 8 (Mus musculus) | BDBM50370584 (Beepen-VK | Betapen-VK | PENICILLIN V | Penapar-VK...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 4.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wilkes University Curated by ChEMBL | Assay Description Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 mins | Drug Metab Dispos 41: 791-800 (2013) Article DOI: 10.1124/dmd.112.049569 BindingDB Entry DOI: 10.7270/Q2TF003W | |||||||||||
More data for this Ligand-Target Pair |